FluoreMAG®
We offer fluorescent tagged nanoparticles called FluoreMAG®.
- Two new products are available, using Fluorescein isothiocyanate (FITC) [Exc = 493 nm/ Emmax = 518 nm] and tetramethylrhodamine B isothiocyanate (TRITC) [Exc = 550 nm/ Emmax = 572 nm] tagged nanoparticles.
- These are tagged with magnetite nanoparticles.
- These materials can be used in the same way as the standard dextran nanoparticles.
- The fluorescence of TRITC functionalised FluoreMAG®A shows only slight changes over the pH range 3-9. For FITC functionalised FluoreMAG®B then the maximum intensity is at a pH above 7.
- The colloids are thermally stable at standard temperatures and neutral pH. Only at elevated pH >9 and elevated temperatures is there a risk for hydrolysis of the thiocarbamoyl linkage.
- Tagged FluoreMAG® nanoparticles are ideal for identification of the endocytotic system as the process can be followed by fluorescence experiments.
Dependence of fluorescence of FITC-dextran (top) and TRITC-dextran (bottom) with pH in the range 4-9
| Product | Dextran (kDa) |
Tag | Core size (mm) |
Hydrodynamic size (nm) |
ζ-potential (mV) |
Fe (mg/ml) |
Solvent |
|---|---|---|---|---|---|---|---|
| FluoreMAG®A | 40 | TRICT | 8.0 | 50 | +5 | 10 | dH2O |
| FluoreMAG®B | 40 | FITC | 8.0 | 50 | +5 | 10 | dH2O |
Customised particles and colloids can prepared including different dextran molecular weights and concentration.
We are happy to accept speculative enquiries about the range of materials and expertise available in our company.
